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The Nobel Prize in Physiology or Medicine 2020 "for the discovery of Hepatitis C virus".


Entry details : D28541


GENERAL INFORMATION
ID D28541; SV 1; linear; genomic RNA; STD; VRL; 189 BP.
Primary AC D28541
Creation Date 12-MAR-1994 (Rel. 38, Created)
Update Date 23-JAN-2011 (Rel. 122, Last updated , Version 0)
Description Hepatitis C virus partial genome, no 5'UTR, partial CDS (Contains: NS5B), no 3'UTR.
Genotype
Deposited n.a.
Provisional n.a.
Confirmed n.a.
Isolate BB7
Keywords partial genome;  partial CDS;  NS5B; 
Organism
OS Hepatitis C virus
OC Viruses;  ssRNA positive-strand viruses, no DNA stage;  Flaviviridae;  Hepacivirus; 
REFERENCES
[1]
1 - 189
RA Hotta H.; 
RL Submitted (15-FEB-1994) to the EMBL/GenBank/DDBJ databases. Contact:Hak Hotta Kobe University School of Medicine, Department of Microbiology; 7-5-1 Kusunoki-cho, Chuo-ku, Kobe, Hyogo 650, Japan
[2]
RA Apichartpiyakul C.;  Chittivudikarn C.;  Miyajima H.;  Homma M.;  Hotta H.; 
RT Analysis of hepatitis C virus isolates among healthy blood donors and drug addicts in Chiang Mai, Thailand
RL J. Clin. Microbiol. 32(9):2276-2279(1994).
RX PUBMED: 7814558  
FEATURES
source
1..189
(189)
db_xref taxon : 11103
db_xref EMBL : D28541
db_xref euHCVdb : DQ835760
mol_type genomic RNA
organism Hepatitis C virus
misc_feature
<1..>189
(189)
note NS5B genotyping region
gene
<1..>189
(189)
locus_tag HCVORF1
CDS
<1..>189
(189)
codon_start offset : 1
db_xref UniProtKB/TrEMBL : Q81731
locus_tag HCVORF1
product Partial HCV polyprotein (contains NS5B).
translation VIEW
mat_peptide
<1..>189
(189)

NS5B
function NS5B protein coding sequence (ns5b sequence)
locus_tag HCVORF1
product NS5B protein. Produced by proteolytic processing by the HCV NS3 protease. NS5B is a RNA-dependent RNA polymerase that plays an essential role in virus replication
prod_ft
chain 1..63  (63) RNA-dependent RNA polymerase (NS5B protein) (P68)
standard_name NS5B
SEQUENCES
Sequence VIEW
Translation(s)
locus_tag HCVORF1 VIEW

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