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The Nobel Prize in Physiology or Medicine 2020 "for the discovery of Hepatitis C virus".


Entry details : AY685034


GENERAL INFORMATION
ID AY685034; SV 1; linear; genomic DNA; STD; VRL; 321 BP.
Primary AC AY685034
Creation Date 31-JUL-2005 (Rel. 84, Created)
Update Date 23-JAN-2011 (Rel. 122, Last updated , Version 0)
Description Hepatitis C virus partial genome, no 5'UTR, partial CDS (Contains: NS5B), no 3'UTR.
Genotype
Deposited 1
Provisional n.a.
Confirmed n.a.
Isolate M7747N
Keywords partial genome;  partial CDS;  NS5B; 
Organism
OS Hepatitis C virus
OC Viruses;  ssRNA positive-strand viruses, no DNA stage;  Flaviviridae;  Hepacivirus; 
REFERENCES
[1]
1 - 321
RA Njouom R.;  Pasquier C.;  Ayouba A.;  Tejiokem M.C.;  Vessiere A.;  Mfoupouendoun J.;  Tene G.;  Eteki N.;  Lobe M.M.;  Izopet J.;  Nerrienet E.; 
RT Low risk of mother-to-child transmission of hepatitis C virus in Yaounde, Cameroon: the ANRS 1262 study
RL Am. J. Trop. Med. Hyg. 73(2):460-466(2005).
RX PUBMED: 16103623  
[2]
1 - 321
RA Njouom R.;  Pasquier C.;  Ayouba A.;  Eteki N.;  Mfoupouendoun J.;  Tene G.;  Tedjiokem M.;  Lobe M.;  Thonnon J.;  Izopet J.;  Nerrienet E.; 
RL Submitted (13-JUL-2004) to the EMBL/GenBank/DDBJ databases. Laboratory of Virology, Toulouse University Hospital, Hopital Purpan, place Baylac, TSA 40031, Toulouse F-31059, France
FEATURES
source
1..321
(321)
country country : Cameroon
sub-region :
db_xref taxon : 11103
db_xref EMBL : AY685034
db_xref euHCVdb : AM910652
mol_type genomic DNA
note genotype: 1
organism Hepatitis C virus
misc_feature
<1..290
(290)
note NS5B genotyping region
gene
<1..>321
(321)
locus_tag HCVORF1
CDS
<1..>321
(321)
codon_start offset : 3
db_xref UniProtKB/TrEMBL : Q49NN4
locus_tag HCVORF1
product Partial HCV polyprotein (contains NS5B).
translation VIEW
mat_peptide
<1..>321
(321)

NS5B
function NS5B protein coding sequence (ns5b sequence)
locus_tag HCVORF1
product NS5B protein. Produced by proteolytic processing by the HCV NS3 protease. NS5B is a RNA-dependent RNA polymerase that plays an essential role in virus replication
prod_ft
chain 1..106  (106) RNA-dependent RNA polymerase (NS5B protein) (P68)
standard_name NS5B
SEQUENCES
Sequence VIEW
Translation(s)
locus_tag HCVORF1 VIEW

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