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The Nobel Prize in Physiology or Medicine 2020 "for the discovery of Hepatitis C virus".

Entry details : AJ401097

[General] [References] [Features] [Sequences] [Text Entry]    [LANL]
GENERAL INFORMATION
ID AJ401097; SV 1; linear; genomic RNA; STD; VRL; 554 BP.
Primary AC AJ401097
Creation Date 12-NOV-2000 (Rel. 65, Created)
Update Date 23-JAN-2011 (Rel. 122, Last updated , Version 0)
Description Hepatitis C virus partial genome, no 5'UTR, partial CDS (Contains: E1), no 3'UTR.
Genotype
Deposited 4a
Provisional n.a.
Confirmed n.a.
Isolate FrSSD120
Keywords partial genome;  partial CDS;  E1; 
Organism
OS Hepatitis C virus subtype 4a
OC Viruses;  ssRNA positive-strand viruses, no DNA stage;  Flaviviridae;  Hepacivirus; 
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REFERENCES
[1]
1 - 554
RA Deny P.; 
RL Submitted (12-JUN-2000) to the EMBL/GenBank/DDBJ databases.
[2]
1 - 554
RA Morice Y.;  Roulot D.;  Grando V.;  Stirnemann J.;  Gault E.;  Jeantils V.;  Bentata M.;  Jarousse B.;  Lotholary O.;  Pallier C.;  Deny P.; 
RT Phylogenetic analyses confirm the high prevalence of hepatitis C virus (HCV) type 4 in the Seine-Saint-Denis district (France) and indicate seven different HCV-4 subtypes linked to two different epidemiological patterns
RL J. Gen. Virol. 82(Pt 5):1001-1012(2001).
RX PUBMED: 11297675  
[General] [References] [Features] [Sequences] [Text Entry]    [LANL]
FEATURES
source
 1..554
(554)
country country : Democratic Republic of the Congo
sub-region :
db_xref taxon : 31653
db_xref EMBL : AJ401097
db_xref euHCVdb : FJ462439
mol_type genomic RNA
note Z4 isolate-like
organism Hepatitis C virus subtype 4a
misc_feature
 <1..378
(378)
note C/E1 genotyping region
gene
 <1..>554
(554)
locus_tag HCVORF1
CDS
 <1..>554
(554)
codon_start offset : 1
db_xref UniProtKB/TrEMBL : Q9DWI4
locus_tag HCVORF1
product Partial HCV polyprotein (contains E1).
translation VIEW
mat_peptide
 1..>554
(554)

E1
function E1 protein coding sequence (e1 sequence)
locus_tag HCVORF1
product Envelope glycoprotein 1 (gp31) (E1 protein). Produced by proteolytic processing by the host signal peptidases. E1 forms heterodimers with the viral E2 envelope glycoprotein
prod_ft
chain 1..184  (184) E1 protein
prod_ft
transmem 162..184  (23) Potential transmembrane region of E1
standard_name E1
[General] [References] [Features] [Sequences] [Text Entry]    [LANL]
SEQUENCES
Sequence VIEW
Translation(s)
locus_tag HCVORF1 VIEW
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