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The Nobel Prize in Physiology or Medicine 2020 "for the discovery of Hepatitis C virus".


Entry details : AF271874


GENERAL INFORMATION
ID AF271874; SV 1; linear; genomic DNA; STD; VRL; 411 BP.
Primary AC AF271874
Creation Date 26-SEP-2000 (Rel. 65, Created)
Update Date 23-JAN-2011 (Rel. 122, Last updated , Version 0)
Description Hepatitis C virus partial genome, no 5'UTR, partial CDS (Contains: C, E1), no 3'UTR.
Genotype
Deposited 4
Provisional 4n
Confirmed n.a.
Isolate 1359
Keywords partial genome;  partial CDS;  C;  E1; 
Organism
OS Hepatitis C virus
OC Viruses;  ssRNA positive-strand viruses, no DNA stage;  Flaviviridae;  Hepacivirus; 
REFERENCES
[1]
1 - 411
RA Ray S.C.;  Arthur R.R.;  Carella A.;  Bukh J.;  Thomas D.L.; 
RT Genetic epidemiology of hepatitis C virus throughout egypt
RL J. Infect. Dis. 182(3):698-707(2000).
RX DOI: 10.1086/315786  
PUBMED: 10950762  
[2]
1 - 411
RA Ray S.C.;  Arthur R.R.;  Carella A.;  Bukh J.;  Thomas D.L.; 
RL Submitted (25-MAY-2000) to the EMBL/GenBank/DDBJ databases. Department of Medicine, Johns Hopkins University School of Medicine, 720 Rutland Avenue, Baltimore, MD 21205, USA
FEATURES
source
1..411
(411)
country country : Egypt
sub-region : Dakahlya governorate
db_xref taxon : 11103
db_xref EMBL : AF271874
db_xref euHCVdb : FJ462441
mol_type genomic DNA
note genotype:4 alpha
organism Hepatitis C virus
misc_feature
<1..>411
(411)
note C/E1 genotyping region
gene
<1..>411
(411)
locus_tag HCVORF1
CDS
<1..>411
(411)
codon_start offset : 1
db_xref UniProtKB/TrEMBL : Q9E2J1
locus_tag HCVORF1
product Partial HCV polyprotein (contains C, E1).
translation VIEW
mat_peptide
<1..42
(42)

C
function C protein coding sequence (c sequence)
locus_tag HCVORF1
product RNA binding nucleocapsid protein (p21) (capsid) (core protein) (nucleocapsid) (C protein). Produced by proteolytic processing by the host signal peptidases
prod_ft
chain 1..14  (14) C protein
standard_name C
mat_peptide
43..>411
(369)

E1
function E1 protein coding sequence (e1 sequence)
locus_tag HCVORF1
product Envelope glycoprotein 1 (gp31) (E1 protein). Produced by proteolytic processing by the host signal peptidases. E1 forms heterodimers with the viral E2 envelope glycoprotein
prod_ft
chain 15..137  (123) E1 protein
standard_name E1
SEQUENCES
Sequence VIEW
Translation(s)
locus_tag HCVORF1 VIEW

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