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The Nobel Prize in Physiology or Medicine 2020 "for the discovery of Hepatitis C virus".


Entry details : AF271815


GENERAL INFORMATION
ID AF271815; SV 1; linear; genomic DNA; STD; VRL; 340 BP.
Primary AC AF271815
Creation Date 20-SEP-2000 (Rel. 65, Created)
Update Date 23-JAN-2011 (Rel. 122, Last updated , Version 0)
Description Hepatitis C virus partial genome, no 5'UTR, partial CDS (Contains: NS5B), no 3'UTR.
Genotype
Deposited 4
Provisional 4o
Confirmed n.a.
Isolate 2153
Keywords partial genome;  partial CDS;  NS5B; 
Organism
OS Hepatitis C virus
OC Viruses;  ssRNA positive-strand viruses, no DNA stage;  Flaviviridae;  Hepacivirus; 
REFERENCES
[1]
1 - 340
RA Ray S.C.;  Arthur R.R.;  Carella A.;  Bukh J.;  Thomas D.L.; 
RT Genetic epidemiology of hepatitis C virus throughout egypt
RL J. Infect. Dis. 182(3):698-707(2000).
RX DOI: 10.1086/315786  
PUBMED: 10950762  
[2]
1 - 340
RA Ray S.C.;  Arthur R.R.;  Carella A.;  Bukh J.;  Thomas D.L.; 
RL Submitted (25-MAY-2000) to the EMBL/GenBank/DDBJ databases. Department of Medicine, Johns Hopkins University School of Medicine, 720 Rutland Avenue, Baltimore, MD 21205, USA
FEATURES
source
1..340
(340)
country country : Egypt
sub-region : Sharm El Sheikh governorate
db_xref taxon : 11103
db_xref EMBL : AF271815
db_xref euHCVdb : FJ462440
mol_type genomic DNA
note genotype:4 beta
organism Hepatitis C virus
misc_feature
1..340
(340)
note NS5B genotyping region
gene
<1..>340
(340)
locus_tag HCVORF1
CDS
<1..>340
(340)
codon_start offset : 2
db_xref UniProtKB/TrEMBL : Q9E2Q0
locus_tag HCVORF1
product Partial HCV polyprotein (contains NS5B).
translation VIEW
mat_peptide
<1..>340
(340)

NS5B
function NS5B protein coding sequence (ns5b sequence)
locus_tag HCVORF1
product NS5B protein. Produced by proteolytic processing by the HCV NS3 protease. NS5B is a RNA-dependent RNA polymerase that plays an essential role in virus replication
prod_ft
chain 1..113  (113) RNA-dependent RNA polymerase (NS5B protein) (P68)
standard_name NS5B
SEQUENCES
Sequence VIEW
Translation(s)
locus_tag HCVORF1 VIEW

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